On the Sites of Attachment and Reaction of Aldehyde Dehydrogen Ases.

نویسندگان

  • M W Nirenberg
  • W B Jakoby
چکیده

Both samples were then dialyzed versus demineralized water in the cold and aliquots withdrawn at intervals for viscosity and other measurements. After three hours, the viscosity of the control started to rise sharply, the value of [v ] reaching 24 in 24 hr. In contrast to this, the enzyme-treated sample showed no significant changes in either viscosity or rotation during the period of the dialysis, [v] being 13.1 after 24 hr. A slight increase was noted in the optical rotation of the control, and the possible significance of this is under investigation. The results clearly demonstrate that the action of trypsin prevents end-to-end polymerization without appreciably altering the dimensions of the TC macromolecules.

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عنوان ژورنال:
  • Proceedings of the National Academy of Sciences of the United States of America

دوره 46 2  شماره 

صفحات  -

تاریخ انتشار 1960